The 7 Best Mouse for Carpal Tunnel In 2021

Best Mouse for Carpal Tunnel

Do you feel shockwaves in your fingers that move up to your arms while using a mouse? Or, do any of your fingers itches or go numb while trying to hold your mouse for a long time?

If yes, you are probably facing Carpal Tunnel Syndrome.

It happens when you use a mouse with bad ergonomics for long hours. It affects your median nerve containing carpel tunnel which is responsible for controlling movement and feelings of your thumbs.

There are mice available in the market designed specifically for carpel tunnel syndrome. But you need an eagle’s eye to separate the wheat from the chaff.

Before we jump into the products list, let’s start with two most important questions.

What is Carpal Tunnel?

Carpal Tunnel Syndrome

It’s a passage for median nerve inside the wrist that goes from our hand to arm. Carpal Tunnel Syndrome is nothing but compression of that median nerve due to heavy use of mouse or keyboard coupled with bad working postures. Repetitive strain injury can also lead to increased pressure on Carpal Tunnel which triggers the syndrome in return.  

What Type Of Mouse Is Best For Carpal Tunnel?

Any mouse that can minimize the risk of thumb tendonitis can be a solution for Carpal Tunnel. Usually, experts suggest using a Trackball Mouse with an exposed ball on the top with upside-down ergonomics. They provide smooth and precise movement to reduce pressure on your wrist and arm.

Having said that, let’s jump into the list of best mice for fighting carpal tunnel syndrome.

7 Best Mouse For Carpal Tunnel

1. Jelly Comb Wireless

Jelly Comb Wireless

If you’ve been facing pain in your wrists, it will get better once you start using this perfectly sculpted mouse. Jelly Comb has a much healthier position for your wrist that keeps your pain away. The comfortable ergonomic design comes with a surprisingly silent operation. It takes very little pressure to depress the buttons and it does not produce any loud noise.

The forward/back buttons offer a tactile feeling thereby making your navigation easier than before. You can change the DPI setting through a small button present behind the scroll wheel and it doesn’t feel in the way at all.

Set the numbers high if you want speed and the opposite if you want precision. The wheel is made up of soft rubber material with fine lines on it to provide more traction but your fingers can barely feel them during the operation.

However, it could feel big for users with small hands. This Jelly Comb wireless mouse is half an inch tall and long for small palms. So if you may need a wrist rest to comfortably reach its end.

Nevertheless, you won’t complain because of its effortless glides without any jump over the screen. The mouse well proves it’s worth ergonomically when you try to move left to right on a 24-inch screen without moving your wrist.


  • Smooth Glides
  • Effortless clicks
  • Tilt ergonomics
  • Quite operation


  • Too big for small hands

2. Logitech M570

Logitech M570

Logitech M570 offers you more travel distance with less wrist and elbow movements. Reclaim any position on your screen with your thumb. Even if you have three screens for horizontal display, it can glide through them without being picked up in between.

Logitech M570 is highly compatible with any system. As it is wireless, you have to take the battery commitment thing seriously. But in return, it will offer you impeccable Bluetooth connectivity and tracking functionality.

Most wireless mice have range issues whereas this one can draw connectivity even from a distance of 3 feet.

Your clicks register with just a minimum push of a button and tracking is barely spotty. It is a best practice to clean the horrid junk that builds up inside the wheel with time. In this regard, it is easy to clean, just like any mechanical mouse by taking the wheel out using a pen or pencil.

For regular laser mouse users, it will take some time to get adjusted with its ergonomics. But once you get a hold of it, you will love the way it will allow you to move around the screen without having to pause or stretch your hand out.


  • More travel distance per unit of mouse effort
  • Easy to clean
  • Compatible with Mac and Windows


  • Not so compatible with Catalina Machines

3. Delux Wired

Delux Wired

This mice on our list is definitely a head-turner. The matte black velvet-like color is very attractive and draws public attention. The clicks produced are quite and can barely make people annoy around you.

It will completely change how you feel about using a mouse for 10-18 hours. Users struggling with tendinitis and carpal tunnel find it extremely useful. It is solidly made and can be your travel-friendly companion if wrapped well.

If you like wired mouse over a wireless one for its sturdiness and hassle-free longtime use, you are definitely going to love it. It is lightweight, well-built, and feels great on your hand.

The buttons are optimally positioned to lower your carpal tunnel syndrome and it works well on any surface without any pad.

As it is a vertical mouse, you may feel like pushing it away while resting your palm on it. Also, you can easily turn RGBs off with a click but that won’t work on any Mac device. You may require a custom button integration for it. 

You may feel a little awkward placing your thumb over it. A button over your thumb gets touchy and makes it difficult to autorun sometimes. Otherwise, it’s a perfect masterpiece.


  • Lightweight and well-built
  • Works without any driver
  • Switch on/off RGB


  • Not compatible with Mac 

4. Anker Optical USB Wired

Anker Optical USB Wired

Next on our list is the Anker Ergonomic Optical USB Mouse which brings comfort and affordability together. Using the latest technology, this ergonomic vertical mouse allows for a neutral “handshake” position which does not strain your arm or hand.

Even if you have small to medium-sized hands, you can find the buttons just beneath your grasp. Therefore, you can browse the internet or play games for long hours with ease. 

The Anker Ergonomic Vertical mouse also provides dedicated “next” and “previous” buttons which prove to be very useful for those who work at length on their computers.

Unlike the standard mice, this vertical mouse uses 1000/1600 DPI Optical Tracking Technology. That means you will have added sensitivity. And that, in turn, means extra smooth tracking and precision on most surfaces.

The DPI switch also toggles between cursor speeds you can adjust as per your need. The Anker Ergonomic Vertical mouse comes with a warranty of 18 months and a guarantee of lifetime technical support which ensures maximum utility. 


  • Lightweight
  • Easy to Get Adjusted to
  • Affordable


  • Short USB Cable

5. Evoluent VM4S

Evoluent VM4S

It is indeed quite irritating with the pinky always rubbing the mouse pad in standard mice. Evoluent’s answer to that problem is VM4S.

This ergonomic mouse is often recommended by medical practitioners, ergonomists, and physical therapists due to its superior built and added comfort. Evoluent’s patented shape for their ergonomic mice provides a lip on the lowest button to rest your pinky.

The mouse also provides an actual dedicated middle-mouse button, which effectively lowers tendon strain and knuckles pain. 

The sideway inclination might come across as a gimmick but it actually helps the arm maintaining a healthy posture. It balances the wrist to align it more accurately and naturally to the radius and ulna bones.

This mouse also allows the user to customize and adjust the mouse settings. All one needs to do is install the Evoluent Mouse Manager in the computer and configure its buttons. 

The mouse also has optical sensors on the side which allow for pointer speed adjustment from low to high. It also has expansive hardware and software compatibility, meaning you can easily plug it in your system and you’ll be good to go.


  • Unique & Comfortable Design
  • Adjustable Mouse-speed
  • Broad Hardware & Software Compatibility


  • Only For Right-handers

6. J-Tech Wireless  

J-Tech Wireless

If you don’t like the cables that come in the way while trying to make swift moves, this J-Tech Wireless Vertical mouse would be your ideal bet.

This ergonomic mouse for carpal tunnel comes with a Dongle Transceiver which allows wireless connection to your computer. The included detachable palm-rest which can be used as per the users’ preferences makes the mouse a very convenient one.

Without an unnecessarily gaudy body, the mouse provides a rather natural grip to avoid wrist pains or knuckle aches. This vertical mouse comes with adjustable sensitivity where you can choose from various DPI levels like 600, 1000, and 1600.

It also comes with an in-built Optical Tracking Technology, which provides extra sensitivity and precision on any surface. For optimum convenience, the ‘back’ and ‘forward’ buttons are placed near the thumb region. You can customize their configuration anytime though. 

Unlike most wireless mice, this J-Tech Vertical mouse does go to sleep soon and can be easily awakened by a left click. With a massive battery life, this mouse will surely meet all your gaming and other extensive needs. 


  • Wireless USB Dongle
  • Adjustable DPI
  • Free Lifetime Technical Support


  • Extraneously huge ‘Back’ button

7. Perixx Perimice-513  

Perixx Perimice-513

Coated in high-quality rubber, the Perixx Perimice-513 Wired Vertical USB Mouse feels like a dream to hold. The slender design of the mouse does not feel extra bulky and gives off a matte finish look from outside.

The mouse offers a better grip than any other plastic vertical mouse and allows your wrist to stay in its natural position without having to compromise with the device performance.

Easy to use by medium to large hands, the mouse also offers a DPI button which allows a toggle between 1000 and 1600 DPI levels. 

The Perixx Perimice 513 features a blue LED light around the thumb area which is bright enough to locate in the dark or low-light settings without lighting up the entire space.

It comes with an easy Plug and Play set up and is compatible across a wide range of systems. Additionally, if you want to reconfigure the button functions, you can install custom software to remap those buttons. 

With a robust futuristic design and 5 easy-to-access buttons, this Perixx Perimice 513 Wired USB mouse will meet all your needs without causing any strain or discomfort to your body.


  • Rubber Coating for Better Grip
  • LED light
  • Available in Left-Handed Version


  • Not for Small Hands


Indeed these are excellent mice for people struggling with carpal pain. They are also an excellent choice for you if you want to avoid this syndrome down the line. Let us know if you have been using any vertical mouse other than listed above. It will help out other readers too looking to alleviate their pain symptoms for sure.